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of no importance in preventing beriberi? It is impossible to draw

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The theories promulgated as to the cause of pellagra bear a striking

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healthy. The father of Pellagrin 503 is also living. They are better-class

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1 Viz., Pas de Calais, Somme, Aisne, Oise, and Calvados, the last only a Norman de-

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with Bright' s disease and with sclerosis of the aorta and coronary

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false pocket, which was interposed between the intact aortic valves

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In the third series, for purposes of comparison, a study was made

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diabetic with the use of the glucosid phlorizin. The work of Halsey, 6

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in the substance of the heart wall, marked in life by remarkable slow-

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but particularly to Dr. O. VV. Leonard and Dr. J. H. Allen, who have

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heart sounds were distant and blurred, and the heart was beating very rapidly

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strong tobacco, which produces the attack, especially the smoking of

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mined. From this a suitable sample was removed for spectrophoto-

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blood cell. The phenolsulphonephthalein excretion on March 2 was 36 per cent,

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mills that were generally speaking markedly superior to the mills

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irradiates also to the right shoulder, and may even follow the same

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ventricle, and least of all in the right auricle. Thus is explained the

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In the cases associated with general disease the condition may be

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of the temporal lobes. In the corpus callosum and frontal lobes there are

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Cardiac decompensation was present in all of these. In seven the

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with rigors, sweating, rapid wasting, and other symptoms of a septi-

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* 16. Kohler : Berliner klinische Wochenschrift, July 25, 1892, p. 743.

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toms and there is one instance of definite severe attack of pellagra in

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tricuspid valves. This neoplasm is derived from the endocardium and

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Among the evidences of acidosis are a diminished carbon dioxid ten-

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gland occurs as an encapsuled growth. The size varies considerably.

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veins, especially into the external jugular and subclavian, sometimes

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It should be noted that a deficiency disease is something radically

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results are in this respect in accord with those of Leichtenstern. This

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Physical examination showed hypertrichosis, optic atrophy, pupils which

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and death in the state hospital for the insane in November, 1914.

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of cases we as yet know nothing. In a few cases the destructive lesion

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of negativity. One galvanometer was connected with a pair of elec-

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the condition of the patient after an interval without any treatment.

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